ASSESSMENT OF THE CYTOLYTIC POTENTIAL OF A MULTIVIRUS-TARGETED T CELL THERAPY USING A VITAL DYE-BASED, FLOW CYTOMETRIC ASSAY

Assessment of the cytolytic potential of a multivirus-targeted T cell therapy using a vital dye-based, flow cytometric assay

Reliable and sensitive characterization assays are important determinants of the successful clinical translation of immunotherapies.For the assessment of cytolytic potential, the chromium 51 (51Cr) release assay has long been considered the gold standard for testing effector cells.However, attaining the approvals to Exhaust Systems access and use r

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HyQue: evaluating hypotheses using Semantic Web technologies

Abstract Background Key to the success of e-Science is the ability to computationally evaluate expert-composed hypotheses for validity against experimental data.Researchers face the challenge of collecting, evaluating and integrating large amounts of diverse information to compose and evaluate a hypothesis.Confronted with rapidly accumulating data,

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